Cart is empty 
Overview
GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding peptide first identified in human plasma. Research has focused on its role in tissue remodeling, extracellular matrix regulation, wound healing, hair follicle biology, antioxidant activity, and skin regeneration. GHK-Cu levels naturally decline with age, leading to interest in its regenerative and cellular signaling properties.
Mechanism of Action
Research suggests GHK-Cu acts as a signaling peptide that regulates gene expression associated with tissue repair and remodeling. Studies indicate it may promote collagen synthesis, stimulate fibroblast activity, support angiogenesis, enhance antioxidant defenses, and influence wound-healing pathways. GHK-Cu has also been investigated for its effects on hair follicle function and skin regeneration.
Compound Information
Stability Information
- Type: Copper-Binding Tripeptide
- Sequence: Glycyl-L-Histidyl-L-Lysine Copper Complex
- Molecular Formula: C14H24N6O4Cu
- Amino Acids: 3
- Molecular Weight: 401.93 g/mol
- Research Areas: Skin biology, tissue repair, hair research, wound healing
- Room temperature stable (short-term)
- Protect from light
- Avoid repeated freeze-thaw cycles
- Lyophilized: Store at -20°C
- Reconstituted: Store at 2-8°C
Published Studies
- The human peptide GHK and tissue remodeling.
- Gene expression profiling of GHK reveals regenerative activity.
- GHK-Cu stimulates collagen synthesis and dermal remodeling.
- Copper peptide modulation of wound healing and angiogenesis.
- The biological activity of copper peptides in skin regeneration.
- GHK-Cu improves wound contraction and tissue repair.
- Copper peptides and hair follicle biology.
- GHK-Cu as a regulator of antioxidant and anti-inflammatory pathways.
- Copper peptide-induced remodeling of extracellular matrix proteins.
- GHK-Cu activates genes associated with tissue repair and regeneration.
Information provided for educational and research reference purposes only. Studies listed are third-party publications and do not constitute medical advice.