Overview
Overview
Epithalon (Epitalon) is a synthetic tetrapeptide derived from Epithalamin, a naturally occurring peptide complex isolated from the pineal gland. Research has focused on cellular aging, telomere biology, circadian regulation, oxidative stress, genomic stability, and longevity-related pathways. Epithalon has been extensively investigated for its potential influence on telomerase activity and cellular lifespan in experimental models.
Mechanism of Action
Mechanism of Action
Research suggests Epithalon may influence telomerase expression and telomere maintenance, helping regulate chromosomal stability during cellular replication. Studies have also examined its effects on melatonin production, antioxidant defenses, circadian rhythm regulation, gene expression, and cellular stress responses. Research indicates potential involvement in pathways related to healthy aging and cellular homeostasis.
Compound Information
Stability Information
- Type: Synthetic Tetrapeptide
- Sequence: Ala-Glu-Asp-Gly (AEDG)
- Parent Compound: Epithalamin Derivative
- Amino Acids: 4
- Molecular Formula: C14H22N4O9
- Molecular Weight: 390.35 g/mol
- Research Areas: Aging biology, telomeres, circadian rhythm, cellular longevity
- Room temperature stable (short-term)
- Protect from light
- Avoid repeated freeze-thaw cycles
- Lyophilized: Store at -20°C
- Reconstituted: Store at 2-8°C
Published Studies
- The pineal peptide Epitalon activates telomerase and elongates telomeres in human cells.
- Epitalon increases telomere length and extends cellular lifespan.
- Peptide regulation of gene expression during aging.
- Epitalon and longevity pathways in experimental models.
- Pineal peptides and circadian rhythm regulation.
- Effects of Epitalon on chromosome stability and aging.
- Epitalon influences melatonin production and antioxidant systems.
- Telomerase activation and cellular aging research.
- Epithalamin-derived peptides and genomic stability.
- Biological effects of Epitalon in gerontology research.
Information provided for educational and research reference purposes only. Studies listed are third-party publications and do not constitute medical advice.
