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Overview
Glutathione is a naturally occurring tripeptide composed of glutamine, cysteine, and glycine. It is one of the body’s primary intracellular antioxidants and plays a critical role in cellular defense against oxidative stress, detoxification pathways, mitochondrial function, immune regulation, and redox balance. Research has focused on its involvement in aging, metabolic health, liver function, neurological health, and cellular resilience.
Mechanism of Action
Research suggests glutathione functions as a major antioxidant by neutralizing reactive oxygen species (ROS) and maintaining cellular redox homeostasis. It serves as a cofactor for glutathione peroxidase and other antioxidant enzymes, supports detoxification through glutathione conjugation pathways, and helps protect proteins, lipids, and DNA from oxidative damage.
Compound Information
Stability Information
- Type: Endogenous Antioxidant Tripeptide
- Sequence: γ-L-Glutamyl-L-Cysteinylglycine
- Molecular Formula: C10H17N3O6S
- Amino Acids: 3
- Molecular Weight: 307.32 g/mol
- Research Areas: Oxidative stress, detoxification, mitochondrial health, aging
- Room temperature stable (short-term)
- Protect from light
- Avoid repeated freeze-thaw cycles
- Lyophilized: Store at -20°C
- Reconstituted: Store at 2-8°C
Published Studies
- Glutathione metabolism and its implications for health.
- Glutathione deficiency and oxidative stress in disease.
- The antioxidant functions of glutathione in cellular defense.
- Glutathione depletion contributes to oxidative damage and aging.
- Glutathione and mitochondrial function in aging and disease.
- Therapeutic roles of glutathione in oxidative stress-related disorders.
- Glutathione as a regulator of immune system function.
- Cellular redox regulation by glutathione.
- Glutathione and liver detoxification pathways.
- Role of glutathione in protecting against oxidative stress and inflammation.
Information provided for educational and research reference purposes only. Studies listed are third-party publications and do not constitute medical advice.