Overview

 

Insulin-Like Growth Factor-1 (IGF-1) is a naturally occurring peptide hormone primarily produced in the liver in response to growth hormone stimulation. Research has focused on its role in cellular growth, protein synthesis, tissue development, muscle biology, neuroprotection, metabolism, and regenerative processes. IGF-1 is considered one of the primary mediators of growth hormone activity throughout the body.

Mechanism of Action

Research suggests IGF-1 binds to the Insulin-Like Growth Factor-1 Receptor (IGF-1R), activating intracellular signaling pathways including PI3K/Akt and MAPK. These pathways regulate cellular proliferation, protein synthesis, tissue growth, glucose metabolism, and cell survival. Studies have investigated its role in muscle development, tissue repair, nervous system function, and metabolic regulation.

Compound Information

Stability Information

  • Type: Growth Factor Peptide
  • Molecular Formula: C331H525N95O93S7
  • Molecular Weight: 7,649 Da
  • Amino Acids: 70
  • Target: IGF-1 Receptor (IGF-1R)
  • Research Areas: Muscle biology, regeneration, neurobiology, metabolism
  • Room temperature stable (short-term)
  • Protect from light
  • Avoid repeated freeze-thaw cycles
  • Lyophilized: Store at -20°C
  • Reconstituted: Store at 2-8°C

Published Studies

Information provided for educational and research reference purposes only. Studies listed are third-party publications and do not constitute medical advice.